CCN meeting | Emmanuel Procyk (INSERM Lyon, France)

16-12-2021 from 15:00 to 16:00

Frontal cortex dynamics and timescales for decision making

Multiple frontal cortex areas contribute to different aspects of flexible decision making. They also collaborate during this process. Here we will present single unit recordings in monkeys and biophysical simulations showing that some aspects of functional specificity of lateral frontal and midcingulate cortex emerge from differences in neural temporal signatures. Biophysical simulations show that such properties might be explained by differences in inhibitory conductances leading to dynamical coding or metastable dynamics, and thus to different capacities for temporal integration. Fast spiking and regular spiking unit activity contribute differently to flexibility. In sum, experimental and simulation data show how inhibitory control of frontal metastability sets the temporal signature of cognition.